My research focusses on the molecular regulation of T cell development in the thymus, for which I use complementary computational and experimental approaches, including single cell multiomics and spatial technologies.

My research aims to better understand the molecular regulation of T cell development in the thymus. During my PhD at King’s College London, I explored the role of several transcription factors in thymopoiesis using knock-out mouse models. For my postdoctoral work in the Taghon lab I then shifted to the investigation of lineage decisions in human T cell development. My current research focusses on the bifurcation and maturation of the αβ and γδ T cell lineages. To address these questions, I use complementary computational and experimental approaches, including single cell multiomics and spatial technologies.

I am a member of the Human Cell Atlas Thymus Network and recently contributed to a collaborative effort to map the molecular and cellular architecture of the human thymus throughout early life. By integrating single-cell and spatial transcriptomics, this work provided critical insights into how the thymic microenvironment shapes T cell development, laying the groundwork for identifying and characterizing tissue niches involved in the establishment of distinct T cell types.