Daniel Nagy

T cells are essential white blood cells from the adaptive immune system – they protect us from pathogens and also kill tumour cells. In contrast to all other blood cells that develop in the bone marrow where also the hematopoietic stem cells (HSC) reside, T cell development takes place within the thymus. A decreased number of T cells, a … Read more

Jolien Van Hulle

Jolien studies αβ vs γδ T cell development at the single cell level.

Tom Putteman

Tom supports the team by providing bioinformatics expertise in the analysis of both bulk and single cell sequencing data.

Imke Velghe

Imke is the lab technician that mainly helps in culturing human pluripotent stem cells to study hematopoiesis and T cell development.

Nina Lambrechts

My research is focused on the transcription factor GATA3, a key regulator of commitment of hematopoietic progenitor cells to the T cell lineage. Interestingly, recurrent mutations have been reported in GATA3 in patients with early T-cell precursor acute lymphoblastic leukemia (ETP-ALL), which is a subtype of T-ALL. So far, it is still unclear whether GATA3 … Read more

Tamara De Vos

Tamara is interested in the involvement of HES genes in T cell development and malignancies.