Els Waegemans
Els studied the role of Notch3 at discrete developmental stages of human T cell development during her PhD in our lab.
Unravelling human T cell development
Els studied the role of Notch3 at discrete developmental stages of human T cell development during her PhD in our lab.
During her postdoc in our lab from 2011 until 2016, Katrien optimised the gene-editing of human embryonic stem cells to study human hematopoeiesis.
Inge was a member of the lab from 2002 until 2016, first as technician, then as PhD student and eventually as post doctoral researcher. During these years, Inge focused on the elucidation of Notch activation during human T cell development.
Imke is the lab technician that mainly helps in culturing human pluripotent stem cells to study hematopoiesis and T cell development.
My research is focused on the transcription factor GATA3, a key regulator of commitment of hematopoietic progenitor cells to the T cell lineage. Interestingly, recurrent mutations have been reported in GATA3 in patients with early T-cell precursor acute lymphoblastic leukemia (ETP-ALL), which is a subtype of T-ALL. So far, it is still unclear whether GATA3 … Read more
Tamara is interested in the involvement of HES genes in T cell development and malignancies.
Juliette studies the molecular mechanisms controlling human alpha-beta and gamma-delta T cell bifurcation.
Steven’s research focuses on the development of novel models to study human hematopoisesis to help better understand genetic immunodeficiencies.
Marieke engages to help the understanding of human T cell specification and commitment.
Matthias studies HES genes in normal and malignant T cell development.