Publications

117 entries « 1 of 6 »

2024

Tougaard, Peter; Pérez, Mario R.; Steels, Wolf; Huysentruyt, Jelle; Verstraeten, Bruno; Vetters, Jessica; Divert, Tatyana; Gonçalves, Amanda; Roelandt, Ria; Takahashi, Nozomi; Janssens, Sophie; Buus, Terkild B.; Taghon, Tom; Leclercq, Georges; Vandenabeele, Peter

Type 1 immunity enables neonatal thymic ILC1 production. Journal Article

In: Science advances, vol. 10, iss. 3, pp. eadh5520, 2024, ISSN: 2375-2548.

Abstract | Links | Altmetric

Assatova, Bimarzhan; Willim, Robert; Trevisani, Christopher; Haskett, Garrett; Kariya, Khyati Maulik; Chopra, Kusha; Park, Sung Rye; Tolstorukov, Michael Yevgeniy; McCabe, Sean M.; Duffy, Jessica; Louissaint, Abner; Huuhtanen, Jani; Bhattacharya, Dipabarna; Mustjoki, Satu; Koh, Min Jung; Powers, Foster; Morgan, Elizabeth A.; Yang, Lei; Pinckney, Brandy; Cotton, Matthew J.; Crabbe, Andrew; Ziemba, Jessica Beth; Brain, Ian; Heavican-Foral, Tayla B.; Iqbal, Javeed; Nemec, Ronald; Rider, Anna Baird; Ford, Josie Germain; Koh, Min Ji; Scanlan, Nora; Feith, David J.; Loughran, Thomas P.; Kim, Won Seog; Choi, Jaehyuk; Roels, Juliette; Boehme, Lena; Putteman, Tom; Taghon, Tom; Barnes, Jeffrey A.; Johnson, P. Connor; Jacobsen, Eric D.; Greenberg, Steven A.; Weinstock, David M.; Jain, Salvia

KLRG1 Cell Depletion As A Novel Therapeutic Strategy In Patients With Mature T-cell lymphoma Subtypes. Journal Article

In: Clinical cancer research : an official journal of the American Association for Cancer Research, 2024, ISSN: 1557-3265.

Abstract | Links | Altmetric

2023

Liang, Kai Ling; Laurenti, Elisa; Taghon, Tom

Circulating IRF8-expressing CD123⁺CD127⁺ lymphoid progenitors: key players in human hematopoiesis. Journal Article

In: Trends in immunology, 2023, ISSN: 1471-4981.

Abstract | Links | Altmetric

Billiet, Lore; Cock, Laurenz De; Sanchez, Guillem Sanchez; Mayer, Rupert L.; Goetgeluk, Glenn; Munter, Stijn De; Pille, Melissa; Ingels, Joline; Jansen, Hanne; Weening, Karin; Pascal, Eva; Raes, Killian; Bonte, Sarah; Kerre, Tessa; Vandamme, Niels; Seurinck, Ruth; Roels, Jana; Lavaert, Marieke; Nieuwerburgh, Filip Van; Leclercq, Georges; Taghon, Tom; Impens, Francis; Menten, Björn; Vermijlen, David; Vandekerckhove, Bart

Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage. Journal Article

In: The Journal of experimental medicine, vol. 220, iss. 6, 2023, ISSN: 1540-9538.

Abstract | Links | Altmetric

Guo, Hao; Xu, Jin; Xing, Peiqi; Li, Qilong; Wang, Donghai; Tang, Chao; Palhais, Bruno; Roels, Juliette; Liu, Jiaxu; Pan, Sa; Huang, Jinyan; Liu, Zhaoqi; Zhu, Ping; Taghon, Tom; Qing, Guoliang; Vlierberghe, Pieter Van; Liu, Hudan

RNA helicase DHX15 exemplifies a unique dependency in acute leukemia. Journal Article

In: Haematologica, 2023, ISSN: 1592-8721.

Abstract | Links | Altmetric

Lambrechts, Nina; Liang, Kai Ling; Velghe, Imke; Strubbe, Steven; Dolens, Anne-Catherine; Taghon, Tom

In Vitro Model Systems to Study Human T Cell Development. Journal Article

In: Methods in molecular biology (Clifton, N.J.), vol. 2580, pp. 335–354, 2023, ISSN: 1940-6029.

Abstract | Links | Altmetric

Provez, Lien; Putteman, Tom; Landfors, Mattias; Roels, Juliette; Reunes, Lindy; T'Sas, Sara; Loocke, Wouter Van; Lintermans, Béatrice; Coninck, Stien De; Thenoz, Morgan; Sleeckx, Wouter; Maćkowska-Maślak, Natalia; Taghon, Tom; Mansour, Marc R; Farah, Nadine; Norga, Koen; Vandenberghe, Peter; Kotecha, Rishi S; Goossens, Steven; Degerman, Sofie; Smedt, Renate De; Vlierberghe, Pieter Van

Pre-Clinical Evaluation of the Hypomethylating Agent Decitabine for the Treatment of T-Cell Lymphoblastic Lymphoma. Journal Article

In: Cancers, vol. 15, 2023, ISSN: 2072-6694.

Abstract | Links | Altmetric

Liang, Kai Ling; Roels, Juliette; Lavaert, Marieke; Putteman, Tom; Boehme, Lena; Tilleman, Laurentijn; Velghe, Imke; Pegoretti, Valentina; de Walle, Inge Van; Sontag, Stephanie; Vandewalle, Jolien; Vandekerckhove, Bart; Leclercq, Georges; Vlierberghe, Pieter Van; Libert, Claude; Nieuwerburgh, Filip Van; Fischer, Roman; Kontermann, Roland E; Pfizenmaier, Klaus; Doody, Gina; Zenke, Martin; Taghon, Tom

Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF. Journal Article

In: Nature immunology, 2023, ISSN: 1529-2916.

Abstract | Links | Altmetric

Pille, Melissa; Avila, John; Sanchez, Guillem Sanchez; Sanchez, Guillem Sanchez; Sanchez, Guillem Sanchez; Sanchez, Guillem Sanchez; Goetgeluk, Glenn; Goetgeluk, Glenn; Munter, Stijn De; Munter, Stijn De; Jansen, Hanne; Billiet, Lore; Weening, Karin; Xue, Haipeng; Bonte, Sarah; Bonte, Sarah; Ingels, Joline; Ingels, Joline; Cock, Laurenz De; Cock, Laurenz De; Pascal, Eva; Pascal, Eva; Deseins, Lucas; Deseins, Lucas; Kerre, Tessa; Kerre, Tessa; Taghon, Tom; Taghon, Tom; Leclercq, Georges; Leclercq, Georges; Vermijlen, David; Vermijlen, David; Vermijlen, David; Vermijlen, David; Davis, Brian; Vandekerckhove, Bart; Vandekerckhove, Bart

The Wiskott–Aldrich syndrome protein is required for positive selection during T-cell lineage differentiation Journal Article

In: Frontiers in Immunology, vol. 14, 2023, ISSN: 1664-3224.

Abstract | Links | Altmetric

de Walle, Inge Van; Lambrechts, Nina; Derveeuw, Anaïs; Lavaert, Marieke; Roels, Juliette; Taghon, Tom

Identification and Purification of Human T Cell Precursors. Journal Article

In: Methods in molecular biology (Clifton, N.J.), vol. 2580, pp. 315–333, 2023, ISSN: 1940-6029.

Abstract | Links | Altmetric

2022

Drobna-Śledzińska, Monika; Maćkowska-Maślak, Natalia; Jaksik, Roman; Kosmalska, Maria; Szarzyńska, Bronisława; Lejman, Monika; Sędek, Łukasz; Szczepański, Tomasz; Taghon, Tom; Vlierberghe, Pieter Van; Witt, Michał; Dawidowska, Małgorzata

Multiomics to investigate the mechanisms contributing to repression of PTPRC and SOCS2 in pediatric T-ALL: Focus on miR-363-3p and promoter methylation. Journal Article

In: Genes, chromosomes & cancer, 2022, ISSN: 1098-2264.

Abstract | Links | Altmetric

Ingels, Joline; Cock, Laurenz De; Mayer, Rupert L; Devreker, Pam; Weening, Karin; Heyns, Kelly; Lootens, Nele; Smet, Saskia De; Brusseel, Marieke; Munter, Stijn De; Pille, Melissa; Billiet, Lore; Goetgeluk, Glenn; Bonte, Sarah; Jansen, Hanne; Lint, Sandra Van; Leclercq, Georges; Taghon, Tom; Menten, Björn; Vermaelen, Karim; Impens, Francis; Vandekerckhove, Bart

Small-scale manufacturing of neoantigen-encoding messenger RNA for early-phase clinical trials. Journal Article

In: Cytotherapy, vol. 24, pp. 213–222, 2022, ISSN: 1477-2566.

Abstract | Links | Altmetric

Kiekens, Laura; Wahlen, Sigrid; Persyn, Eva; Vos, Zenzi De; Taghon, Tom; Vandekerckhove, Bart; Leclercq, Georges

T-BET drives the conversion of human type 3 innate lymphoid cells into functional NK cells. Journal Article

In: Frontiers in immunology, vol. 13, pp. 975778, 2022, ISSN: 1664-3224.

Abstract | Links | Altmetric

Persyn, Eva; Wahlen, Sigrid; Kiekens, Laura; Loocke, Wouter Van; Siwe, Hannah; Ammel, Els Van; Vos, Zenzi De; Nieuwerburgh, Filip Van; Matthys, Patrick; Taghon, Tom; Vandekerckhove, Bart; Vlierberghe, Pieter Van; Leclercq, Georges

IRF2 is required for development and functional maturation of human NK cells. Journal Article

In: Frontiers in immunology, vol. 13, pp. 1038821, 2022, ISSN: 1664-3224.

Abstract | Links | Altmetric

Boehme, Lena; Roels, Juliette; Taghon, Tom

Development of γδ T cells in the thymus – A human perspective Journal Article

In: vol. 61-64, pp. 101662, 2022, ISSN: 1044-5323.

Links | Altmetric

Persyn, Eva; Wahlen, Sigrid; Kiekens, Laura; Taveirne, Sylvie; Loocke, Wouter Van; Ammel, Els Van; Nieuwerburgh, Filip Van; Taghon, Tom; Vandekerckhove, Bart; Vlierberghe, Pieter Van; Leclercq, Georges

TXNIP Promotes Human NK Cell Development but Is Dispensable for NK Cell Functionality. Journal Article

In: International journal of molecular sciences, vol. 23, 2022, ISSN: 1422-0067.

Abstract | Links | Altmetric

Roels, Juliette; Hulle, Jolien Van; Lavaert, Marieke; Kuchmiy, Anna; Strubbe, Steven; Putteman, Tom; Vandekerckhove, Bart; Leclercq, Georges; Nieuwerburgh, Filip Van; Boehme, Lena; Taghon, Tom

Transcriptional dynamics and epigenetic regulation of E and ID protein encoding genes during human T cell development. Journal Article

In: Frontiers in immunology, vol. 13, pp. 960918, 2022, ISSN: 1664-3224.

Abstract | Links | Altmetric

Wahlen, Sigrid; Matthijssens, Filip; Loocke, Wouter Van; Taveirne, Sylvie; Kiekens, Laura; Persyn, Eva; Ammel, Els Van; Vos, Zenzi De; Munter, Stijn De; Matthys, Patrick; Nieuwerburgh, Filip Van; Taghon, Tom; Vandekerckhove, Bart; Vlierberghe, Pieter Van; Leclercq, Georges

The transcription factor RUNX2 drives the generation of human NK cells and promotes tissue residency. Journal Article

In: eLife, vol. 11, 2022, ISSN: 2050-084X.

Abstract | Links | Altmetric

2021

Lorenzi, Lucia; Chiu, Hua-Sheng; Cobos, Francisco Avila; Gross, Stephen; Volders, Pieter-Jan; Cannoodt, Robrecht; Nuytens, Justine; Vanderheyden, Katrien; Anckaert, Jasper; Lefever, Steve; Tay, Aidan P; de Bony, Eric J; Trypsteen, Wim; Gysens, Fien; Vromman, Marieke; Goovaerts, Tine; Hansen, Thomas Birkballe; Kuersten, Scott; Nijs, Nele; Taghon, Tom; Vermaelen, Karim; Bracke, Ken R; Saeys, Yvan; Meyer, Tim De; Deshpande, Nandan P; Anande, Govardhan; Chen, Ting-Wen; Wilkins, Marc R; Unnikrishnan, Ashwin; Preter, Katleen De; Kjems, Jørgen; Koster, Jan; Schroth, Gary P; Vandesompele, Jo; Sumazin, Pavel; Mestdagh, Pieter

The RNA Atlas expands the catalog of human non-coding RNAs. Journal Article

In: Nature biotechnology, vol. 39, pp. 1453–1465, 2021, ISSN: 1546-1696.

Abstract | Links | Altmetric

Strubbe, Steven; Taghon, Tom

Modeling of human T cell development in vitro as a read-out for hematopoietic stem cell multipotency. Journal Article

In: Biochemical Society transactions, vol. 49, pp. 2113–2122, 2021, ISSN: 1470-8752.

Abstract | Links | Altmetric

117 entries « 1 of 6 »